二甲基甲酰胺(DMF)是一种常用的有机溶剂,广泛应用于制药、化学、合成材料等领域。但是,DMF毒性较高,需要注意安全使用。下面是一份关于DMF的英文MSDS报告。
MATERIAL SAFETY DATA SHEET
SECTION 1: PRODUCT AND COMPANY IDENTIFICATION
Product Name: Dimethylformamide (DMF)
CAS Number: 68-12-2
Manufacturer/Supplier: ABC Chemicals Inc.
Address: 123 Main Street, Anytown, USA
Emergency Phone: (800) 555-1234
SECTION 2: HAZARDS IDENTIFICATION
GHS Classification:
Skin corrosion/irritation Category 1B
Serious eye damage/eye irritation Category 1
Specific target organ toxicity (repeated exposure) Category 1
GHS Label Elements: Corrosive, Toxic
Hazards Description:
DMF is corrosive and can cause severe skin and eye irritation. It is also toxic and can cause damage to the liver, kidneys, and nervous system. Prolonged or repeated exposure may cause sensitization of the respiratory tract.
SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS
Chemical Name: Dimethylformamide (DMF)
CAS Number: 68-12-2
Percent: 100%
SECTION 4: FIRST AID MEASURES
Skin Contact: Immediately remove contaminated clothing and rinse skin with water for at least 15 minutes. Seek medical attention if irritation or redness occurs.
Eye Contact: Rinse eyes with water for at least 15 minutes, lifting upper and lower eyelids occasionally. Seek medical attention immediately.
Ingestion: Do not induce vomiting. Rinse mouth with water and seek medical attention immediately.
Inhalation: Move to fresh air immediately. If breathing difficulties persist, seek medical attention.
SECTION 5: FIRE-FIGHTING MEASURES
Fire Hazard: DMF is flammable and may ignite if exposed to heat, sparks, or flames.
Extinguishing Media: Use carbon dioxide, dry chemical, or foam to extinguish fires.
SECTION 6: ACCIDENTAL RELEASE MEASURES
Spill/Leak: Wear protective clothing and equipment. Contain and absorb the spill with an inert material. Dispose of according to local regulations.
SECTION 7: HANDLING AND STORAGE
Handling: Wear protective clothing and equipment when working with DMF. Avoid skin and eye contact. Use in a well-ventilated area.
Storage: Store in a cool, dry, well-ventilated area away from heat, sparks, and flames.
SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Limits:
OSHA Permissible Exposure Limit (PEL): 10 ppm (TWA)
ACGIH Threshold Limit Value (TLV): 10 ppm (TWA)
Personal Protective Equipment:
Eye/Face Protection: Wear chemical safety goggles and a face shield.
Skin Protection: Wear impervious gloves, apron, and boots.
Respiratory Protection: Use a NIOSH-approved respirator with organic vapor cartridges.
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Clear, colorless liquid
Odor: Ammonia-like odor
Melting Point: -61°C (-78°F)
Boiling Point: 153°C (307°F)
Flash Point: 58°C (136°F)
Specific Gravity: 0.944
Vapor Pressure: 3 mmHg at 20°C
SECTION 10: STABILITY AND REACTIVITY
Stability: DMF is stable under normal temperatures and pressures.
Incompatibilities: DMF is incompatible with strong oxidizing agents, acids, and halogens.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides.
SECTION 11: TOXICOLOGICAL INFORMATION
Acute Toxicity:
Oral LD50: 2800 mg/kg (Rat)
Dermal LD50: 4000 mg/kg (Rabbit)
Inhalation LC50: 3600 ppm/4h (Rat)
Chronic Toxicity:
Repeated exposure may cause liver and kidney damage, as well as neurological effects.
SECTION 12: ECOLOGICAL INFORMATION
Ecotoxicity: DMF is toxic to aquatic life.
SECTION 13: DISPOSAL CONSIDERATIONS
Disposal: Dispose of in accordance with local regulations.
SECTION 14: TRANSPORT INFORMATION
Shipping Information: DMF is regulated as a hazardous material for transportation.
SECTION 15: REGULATORY INFORMATION
Regulatory Information: DMF is regulated under OSHA Hazard Communication Standard (29 CFR 1910.1200) and SARA Title III.
SECTION 16: OTHER INFORMATION
The information contained in this MSDS is believed to be accurate and reliable. However, ABC Chemicals Inc. makes no warranty, express or implied, regarding the accuracy or completeness of the information. The user assumes all risks of use, handling, and disposal of the product, and assumes all responsibility for compliance with all applicable laws and regulations.